Deaths from peptic ulceration

Deaths from peptic ulceration.

Deaths due to peptic ulceration can be prevented only by curing the ulcer and preventing the ulcer diathesis permanently by either medical or surgical means. Recurrence of ulcers after drug treatment is a major problem, so continuous treatment is often necessary, but there is no evidence that this decreases mortality. Surgery is the only means of permanently removing the ulcer diathesis in most...

The pathology of peptic ulceration.

is justifiable. A psychiatric opinion is often helpful, but it must be borne in mind that the lesion is never purely hysterical, though there may be a background or ' overlay' of neurosis. If biliary regurgitation is the main complaint then reflux due to hiatus hernia or to obstruction of the stoma must be excluded. As indicated previously, the operation which the writer finds most satisfactory...

The surgery of peptic ulceration.

Cimetidine therapy does not prevent rebleeding from peptic ulceration.

One-hundred and five patients admitted to hospital with symptoms of acute upper gastrointestinal haemorrhage shown at endoscopy to be due to peptic ulceration were entered into a prospective double-blind controlled trial of cimetidine versus placebo therapy. The trial therapy was commenced within 12 hr of admission and continued for 7 days. Cimetidine therapy made no difference to the transfusi...

Serum pyridoxal in active peptic ulceration.

Fasting serum pyridoxal was assayed by an automated microbiological system in 50 patients with endoscopically confirmed active peptic ulceration. Thirty patients had gastric ulceration, 14 had duodenal, four had pyloric canal ulceration, and two had both a gastric and a duodenal ulcer. Serum pyridoxal was below normal in 28 of the gastric ulcer group and in one of the duodenal ulcer group. No d...